产品详情
- ProductSizeAmountActiveMax® Anti-G4S linker μBeads, premium grade (for cells, 5.5 μm)2.5 mg2.5 × 10⁷ beadsActiveMax® Anti-G4S linker μBeads, premium grade (for cells, 5.5 μm)10 mg (2.5 mg × 4)1.0 × 10⁸ beads
背景(Background)
ActiveMax® Anti-G4S linker μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5), and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.
表达区间及表达系统(Source)
ActiveMax® Anti-G4S linker μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm coated with monoclonal Anti-G4S linker Antibody which is a rabbit monoclonal antibody recombinantly expressed from human 293 cells (HEK293). The antibody can specifically recognize the linker of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser.
应用说明(Application)
ActiveMax® Anti-G4S linker μBeads, premium grade (for cells) is designed to positively select cells engineered to express the CARs containing a G4S linker within the scFv. It is used to enrich cells with CAR-containing a G4S linker on the surface.
The Product performance has been carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. For use in clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials used in cell manufacturing of cell-based therapies.* We also carry ActiveMax® Streptavidin μBeads, premium grade (for cells)(Cat. No. MBS-C009), and it can be used for convenient preparation of your own sterile protein/antibody coupled beads for cell-based assay, cell sorting, and other applications. The ActiveMax® Streptavidin μBeads, premium grade can also be used together with other ActiveMax® μBeads, premium grade as Isotype control.
存储(Storage)
This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles after reconstitution. Immediate use after reconstitution is highly recommended.
无菌(Sterility)
Negative
内毒素(Endotoxin)
Less than 0.002 EU per μg by the LAL method.
注意事项(Important Note)
This product is for research use only and not intended for therapeutic or in vivo diagnostic use.
制剂(Formulation)
Please contact us for detailed information.
Contact us for customized product form or formulation.
质量管理控制体系(QMS)
产品展示
典型数据-Typical Data
Please refer to DS document for the assay protocol.
Assay of Anti-G4S linker on the μBeads surface by Flow cytometry. The Anti-G4S linker conjugated on the μBeads (Cat. No. MBS-C022) surface were fluorescently stained using PE Goat anti-Rabbit IgG (H+L) respectively, and then analyzed by flow cytometry (QC tested).
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